Morpheus is a lightweight and easy to use application that can perform fast proteomics database search, even for large human datasets.
Morpheus is designed for tandem mass spectra and high-resolution MS/MS. It enables you to customize the assumed precursor change states and adjust the mass tolerance levels.
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Laser Vision Correction Overview:
Eye diseases, including Cataracts and Macular Degeneration, are caused by a number of conditions or diseases. At present, the treatment mainly depends on drug application to the degeneration process. If you are suffering from any of these conditions, Laser Vision Correction (LVC) is the most effective treatment you can receive.
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Laser Vision Correction has been widely used in treating a variety of eye diseases, such as diopters, myopia, hyperopia, presbyopia, astigmatism, and other diseases. As they possess a number of unique features, we highly recommend that you have Laser Vision Correction done by experienced doctors to avoid any side effects. Besides, Laser Vision Correction patients always reported that they no longer need to spend a lot of money on glasses or contact lenses, they no longer need to stare at a computer monitor, they are more satisfied with the accuracy of their eyesight, and they can enjoy a more comfortable life.
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Laser Vision Correction for Eye Diseases is mainly composed of Laser Technique, Laser Beam Treatment, and Laser Eye Surgery. Laser Technique is used to raise the energy of the laser beams,
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The PEAKS software suite comprises five software tools specifically designed to perform proteomics analysis.
PEAKS software suite is a comprehensive platform that accelerates the experimental data analysis while providing a unified programming environment for data processing.
The PEAKS software suite’s packages are designed to be used together and are…
Platforms: Mac, Windows
JASPER is a huge number of tools – which greatly increases the workload in the statistics. But the advantage is that they are made for the direct use by the scientists. At the moment JASPER provides all the components necessary for EMR on the web, and there is a new version of JASPER in the development phase, where it will be possible to make all the components of the package of JASPER with one click, so the JASPER will be perfectly integrated with MS Excel. So if you already have installed…
PeptideSieve is a standalone open-source application. It implements various protein analysis methods. It is suitable for searching proteins in any type of proteomic projects. PeptideSieve includes several fast databases for peptide, protein, and proteoform identification, including UniProt, UniParc, RefSeq, RefPep.
The tool contains an embedded PCap module, which allows it to operate in batch mode.
Search Proteomes is a peptide database application that enables your users to search the protein and peptide sequences stored on your server by assembling, parsing, comparing with, and searching text files containing peptide sequences. You can also batch upload files through the web-based interface, or through a command line or web script. Search Proteomes supports integration of the output of protein sequence identification tools such as…
Platforms: Windows, Windows 7, Windows ServerA blog for all seasons; A blog for one; A blog for all. As the 11th most informative blog on the planet, I have a seared memory of throwing my Time 2006 Man of the Year Award over the railing at Time Warner Center.
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Monday, August 13, 2016
INNOCENT LEAKERS SENTENCED
Sentencing completes the collapse of the Ruiz administration:
The former deputy mayor of New York City, Keith Evans, got a sentence of five years and four months.
The former New York City police detective Eddie Garces got a four
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Mass spectra preprocessing
MSToF module allows the user to modify in details the Spectrum-to-Peaks
module where you can improve the initial spectra processing.
Raw data import
The raw data import allows you to import and import their formats.
It allows the user to load mass spectra, consider the precursor change states,
and get the m/z peak list. It can compute the precursor for each
multiplexed mass in the spectra, use the chosen search engine
to perform the database search.
The MS/MS generation allow you to export MS/MS spectra in the ProteomeXchange
standard format (XML, MS2XML, MSGF, xml, tsv, sif). With this module, you
will be able to save all the searched spectra to a database.
Morpheus allows you to reorder the precursor scan (tru, mis) or to use any other, before any spectrum analysis and improvement:
For longer precursors, you can split the precursor to two with MassTool (an optional tool). And you can then consider this two mass fragment as one, if the precursor is far enough.
For shorter precursors, MassTool option can be used.
For better quality spectra, you can apply a rescaling tool, that will allow the user to rescale the spectrum to a given profile.
With Morpheus there are many possibilities to optimize the fragment m/z, spectrum or MS/MS spectra to enhance their quality. You can also validate and standardize your search results.
Morpheus is based on an algorithm that compare the “spectrum signature” of a known spectrum against a current one. It uses a modified version of Progenesis.
The Morpheus Tools are the core of the application. They are used by the user during the search:
The MassTools are used for the spectrum processing:
MassTools is a software and a number of software plugins for Morpheus.
It can process files directly or be used to optimize a spectrum for a database search with Morpheus
What’s New In Morpheus?
– High performance
– Precursor change state is customizable
– Peptide search queries can be specified
– Wide variety of vendor and target search databases are supported
– All types of search engine databases can be searched
– Other techniques such as peptide mass fingerprint can be performed
– Run batch mode and execute jobs
– Can search for protein and modified protein, including phosphorylation, acetylation, ubiquitination, myristilation, nicotinamide adenine dinucleotide, *N*-glycosylation, deamidation, oxidation, cysteinylation, and biotinylation
– Customizable to perform either high-resolution MS/MS or tandem mass spectrometry
– Full functionality of the mass spectrum display is supported, including database search results, spectrum generation, and precursor and product ion spectra
– Compatible with all major operating systems such as Windows 7, Mac OS X, and Linux
– No dependencies
– Quick start tutorial
– Extremely easy to use
– Easy database installation
– Free to use
Change state to can_resolve_multiple_states
Using the precursor change state
Compatible with all major operating systems such as Windows 7, Mac OS X, and Linux
A tool for fast identification of bacterial proteins from MS-based proteomics data.
Proteotyper is a tool for the rapid identification of bacterial proteins from their tandem mass spectra (MS/MS spectra). The user need only submit the protein sequences/ID’s along with the tandem mass spectra to the server, which will report the search results back to the user’s email in the format of tables.
Proteotyper is designed for the
Windows 7 64bit or later, Intel i3 or AMD equivalent
1280×720 HD resolution
HD DVI-D or HDMI display adapter (not included)
Core2Quad, Core2Extreme or Core i7-8xxx series
5.1 or higher surround sound, system sounds muted.
HD DVI-D or HDMI