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Epson f-860 toner cartridge r2200 Daa2l0zdMethotrexate therapy in the management of nonalcoholic fatty liver disease.
The pathogenesis of nonalcoholic fatty liver disease (NAFLD) is still largely unknown. However, the proinflammatory state associated with obesity and other metabolic disorders may explain the development of NAFLD. Methotrexate (MTX) can improve hepatic steatosis and possibly some of the insulin resistance. This study aimed to investigate the efficacy of MTX in the treatment of NAFLD. Thirty-five patients with biopsy-proven NAFLD were enrolled in this prospective controlled clinical trial. Patients were randomized into 2 groups: MTX (group 1, n = 19) and placebo (group 2, n = 16) for 6 months. Liver biopsy was repeated at the end of the study. In group 1, MTX was administered orally at a dose of 15 mg once weekly. Patients in group 2 received placebo. Clinical and biochemical parameters, serum lipid profile, homeostasis model assessment (HOMA), anthropometry, and dietary intake were measured at baseline and the end of the study. Both groups were comparable at baseline. We observed a significant decrease in body weight and body mass index in group 1, but no significant change in these parameters in group 2. MTX administration was associated with a significant decrease in serum cholesterol, low-density lipoprotein cholesterol (LDL-C), and very low-density lipoprotein cholesterol. The HOMA-IR and HOMA-B increased significantly in group 1. The improvement of HOMA was comparable in the 2 groups. MTX therapy is an effective treatment for NAFLD in obese, nondiabetic patients.Q:

Solving a linear system of equations without R

I want to solve a system of linear equations where the unknowns are between 0 and 1 and both the number of equations and the number of unknowns is a bit larger than one.
I see 3 options:
1) Use R, e.g. via the function solve from the package Matrix.
2) Use the function solve from the function lsei from the package lsei.
3) Use the function dgesv from the package LAPACK. This may be the most efficient way, but I am just a beginner in matrix algebra and I would like to have a cross-platform solution.
I know that with option

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